A topical skin cancer treatment removed tumors in the majority of patients in a study in Rome, according to The Telegraph.
The topical treatment is for basal cell carcinoma, the most common form of skin cancer. The cream kills tumors using rhenium-188, a radioactive isotope, and does not damage the skin around it.
In a study of 1,000 patients, the researchers reported that it removed the tumors in 95% of patients after one treatment.
An Alternative to Surgery?
Basal cell carcinoma, which grows slowly and is the least likely form of skin cancer to spread, is usually surgically removed. The topical treatment would offer an alternative so that patients with tumors on their faces could avoid scarring.
Dr. Ulli Köster, a researcher at the Institut Laue-Langevin in France, where the radioactive material is produced, said, “Typically this disease is treated by surgery, and since it doesn’t metastasize this is usually okay. But the problem is if the tumor is on the face, on the nose, ear or somewhere, it is strongly disfiguring – someone can have a big scar or lose half of his face.”
During treatment with the cream, a base layer is applied to the skin to protect the healthy cells from the radioactive isotope. The radioactive cream is then applied over the base and targets the tumor. Dr. Köster described it as “a localized radiation therapy.”
The researchers believe it could improve patients’ quality of life, because they could avoid facial scarring.
“I would imagine we are not talking about a major breakthrough but another option. It is nice to have a menu of different options for people, particularly with things that can have a cosmetic impact,” said Martin Ledwick, of Cancer Research UK.
According to the report, the next step will be larger trials in Germany. There was no word on whether trials were planned for the United States.